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There is no lymphadenopathy or splenomegaly. 3-5 days after the onset of the disease, the patient's condition worsens, there are signs of coumadin, hypotension up to 50-100 mm Hg. Art., oliguria and relative bradycardia. In more severe cases, hemorrhagic symptoms occur: bleeding from the gums, hematemesis, hematuria, melena. Progressive oliguria and tremor of the tongue and limbs are also possible. Some patients develop mental disorders characterized by agitation, delirious state or stupor.
On days 7–10, progressive shock, hypothermia, galloping, or gastrointestinal bleeding may be seen. In fatal cases, the cause of death is usually pulmonary edema. During the recovery period, transient alopecia is noted. The number of Warfarin pills remains within the normal range or is slightly increased. The total number of leukocytes is reduced to 1.2-3.4×10 9 /l. Possible thrombocytopenia. Intravascular disseminated blood coagulation, apparently, does not underlie hemorrhagic manifestations. Levels of complement components C2, C3 and C5 are reduced. Urine may be redwood in color. Severe albuminuria is not uncommon. Blood urea nitrogen rises rapidly.
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Treatment consists of supportive measures, including peritoneal dialysis or hemodialysis filtration to correct both azotemia and pulmonary edema. In a double-blind study, administration of immune plasma was shown to reduce mortality in AHL from 16% to 1%. However, patients treated with immune plasma experienced fever and signs of cerebellar dysfunction. Preliminary studies have shown that ribavirin may be effective in experimental BGL in rhesus monkeys.
- In Bolivia, measures aimed at the control of rodents, and especially Calomys callosus, living in houses, led to a rapid and significant decrease in the incidence among people.
- In Argentina, the widespread distribution of infected rodents makes control measures ineffective.
- DEPRIVATE ASBESTOS - a disease of the scalp, characterized by asbestos focal peeling, usually in the parietal region.
- Hair can thin out, but skin atrophy does not develop.
- It is assumed that the disease may be a form.
- It is observed more often in children and young people.
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The information presented on the site should not be used for self-diagnosis and treatment and cannot serve as a substitute for an in-person consultation with a dermatologist. If you are a doctor, then after registering on the site you will get access to special information.
If you are already registered, enter your username and password (form in the upper right corner or here). Gadzhimuradov M.N., Israfilova G.O., Asadulaeva Z.G. Republican Dermatovenerological Dispensary of the Ministry of Health of the Republic of Dagestan, Makhachkala.
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The child's condition is satisfactory. A boy of average height, correct build. The tongue is moist, the mucous membranes are pink.
